History[ edit ] Rosalyn Sussman Yalow and Solomon Berson are credited with the development of the first immunoassays in the s.
Most, though not all, immunoassays involve chemically linking antibodies or antigens with some kind of detectable label. In addition, the enzyme immunoassay technique has been refined into a low cost and portable EIA kit which can be used for a large population in places with low resources.
Cloud-Clone Diagnostic Reagents Institute, a subsidiary company of Cloud-Clone Corp, has developed a range of sandwich chemiluminescence enzyme immunoassay kits used to quantitatively measure the tumor markers for clinical diagnosis.
An appropriate method should be determined for each assay system. Principle[ edit ] Immunoassays rely on the ability of an antibody to recognize and bind a specific macromolecule in what might be a complex mixture of macromolecules.
Pierce of Los Angeles, California 7and L. The enzymes which are commonly used in this process include glucose oxidase and alkaline phosphase.